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Experts say that the patients’ muscles have weakened up to 40 % when they return to sports. Bedi and mendias from the university of michigan revealed the use of human growth hormone (hgh) in patients who had undergone acl surgery. Hgh, basically a hormone in the human body, stimulates cell growth and cell degeneration. Using aseptic techniques, a 10 ml syringe was filled with a solution of 12. 5% dextrose solution and 1 iu of human growth hormone (hgh) for injection into the first metatarsophalangeal joint (intraarticular). Co-injection of ha and recombinant human growth hormone (gh) was found more effective in modifying structures and symptoms when compared to the injections of ha alone in oa-induced rabbits 6). Growth itself is an intrinsic property of all cells, but the growth hormone does have its greatest influence on certain tissues, especially cartilage. Gigantism and acromegaly were what originally made people interested in looking for a growth hormone, and these are characterized by continued, exaggerated enlargement of bones and cartilage. The human data on hgh for osteoarthritis. There are only a handful of papers published on humans where hgh for osteoarthritis was the treatment. For example, this paper where the physicians added hgh to prp and compared it to prp alone (6). Recombinant human growth hormone (rhgh) has been in use for 30 years, and over that time its safety and efficacy in children and adults has been subject to considerable scrutiny. Human growth hormone is a protein-based poly-peptide hormone. It stimulates growth and cell reproduction and regeneration in humans and other animals. It is a 191-amino acid, single-chain polypeptide hormone that is synthesized, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland. Growth hormone is used clinically to treat children's growth disorders and adult growth hormone deficiency. Another potential danger is that many of the illicit sales are of human tissue-derived pituitary growth hormone, which has been removed from the market because it has the potential to contain the pathogen that causes creutzfeldt-jakob disease. And yet, some of this type of hormone is still available in eastern europe and through the internet. I want it for its direct benefits of bone growth and maintenance. Human growth hormone and aging to evaluate the safety and efficacy of gh in healthy older people, a team of researchers reviewed 31 high-quality studies that were completed after 1989. Each of the studies was small, but together they evaluated 220 subjects who received gh and 227 control subjects who did not get the hormone. Local injection of growth hormone for temporomandibular joint osteoarthritis intra-articular injection of gh improved oa scores in rat tmjs in both cartilage and subchondral bone of the condyles without affecting condylar bone growth. It is well known that in osteoarthritis, chondrocytes retain their proliferative activity. Osteophytes or bone spurs are an example of this activity. Another example of adult articular cartilage cells’ replication is acromegaly. In this condition the body produces an excessive amount of human growth hormone and with it, articular cartilage
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